Can Resistance Exercise Alter Irisin Levels and Expression Profiles of FNDC5 and UCP1 in Rats?
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چکیده
منابع مشابه
Can Resistance Exercise Alter Irisin Levels and Expression Profiles of FNDC5 and UCP1 in Rats?
BACKGROUND Irisin is a new myokine secreted from the skeletal muscle and appears to affect the metabolism of adipose tissue. OBJECTIVES The mechanisms of cellular and molecular identification by which exercise training exerts its benefits remain unclear and are under investigation. METHODS We examined the effect of 8-week resistance exercise on plasma irisin levels and expression profiles o...
متن کاملAre Heart Muscle Irisin Levels and FNDC5 Gene Expression Regulated by Endurance and Resistance Exercises?
Background. Irisin is the result of the proteolysis of fibronectin type III domain-containing protein 5, the levels of which are determined by physical activity. Objective(s). This study aims to identify changes in FNDC5 gene expression and the heart muscle irisin levels in male rats following 8 weeks resistance and endurance training. Methods. Fifteen male rats (10-12 weeks old and 331.8&plu...
متن کاملIrisin and FNDC5 in retrospect
FNDC5 (fibronectin domain-containing [protein] 5) was initially discovered and characterized by two groups in 2002. In 2011 FNDC5 burst into prominence as the parent of irisin, a small protein containing the fibronectin type III domain. Irisin was proposed to be secreted by skeletal muscle cells in response to exercise, and to circulate to fat tissue where it induced a transition to brown fat. ...
متن کاملمعرفی هورمون ورزش (Irisin)
Introduction: Almost 15% of world populations suffer from obesity. Obesity and insulin resistance are the key pathogenesis risk factors of type 2 diabetes mellitus (T2DM) and cardiovascular disease. Exercise training can accelerate metabolism and help to prevent the obesity and diabetes through induction of Irisin and triggers conversion of white adipose tissue to brown adipose tissue. Metho...
متن کاملIrisin/FNDC5--An updated review.
OBJECTIVE The irisin, recently identified novel molecule, has been shown to be secreted from fibronectin type III domain containing 5 (FNDC5) of skeletal muscle by an unknown protease. It has been proposed that this molecule plays an important role in converting the white adipose tissue to brown adipose tissue and regulating the energy expenditure. Apart from this, its expression and role in va...
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ژورنال
عنوان ژورنال: Asian Journal of Sports Medicine
سال: 2016
ISSN: 2008-000X,2008-7209
DOI: 10.5812/asjsm.35205